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In the kidneys of STZ-induced diabetic mice and HK-2 cells cultured with high glucose, iron overload, decreased antioxidant capacity and high rates of ROS production and lipid peroxidation are the signature changes of ferroptosis [225, 228]
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Glutathione, a naturally occurring antioxidant, plays a crucial role in protecting cells from damage caused by free radicals
Those using insulin or sulfonylureas need medical guidance when adding these peptides
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